Pradaxa Versus Warfarin

Pradaxa and Warfarin and are both anticoagulants that inhibit the blood´s ability to clot. However, Pradaxa and Warfarin perform this job in different ways. Warfarin interferes with chemical reactions that are dependent on vitamin K. Warfarin, on the other hand, works by attaching to thrombin (a clotting agent) so that it cannot attach to anything else.

Why the Difference Between the Two Drugs Is Important

While the end result of both Pradaxa and warfarin is decreased clotting, warfarin has the significant advantage of being reversible. If a patient starts bleeding or warfarin´s effects need to be reversed for any other reason, doctors have many options to do so. One common approach is administering vitamin K. The vitamin K overrides the effects of warfarin, and blood clots as it normally would.

In contrast, Pradaxa has no readily available reversal agent. Instead, patients must wait for the drug´s effects to naturally wear off as it is processed by the body. This leaves patients in danger of bleeding out even in an emergency situation.

Further complicating the lack of a reversal agent is that Pradaxa is mostly processed by the kidneys. This means that many patients, including those with impaired kidney function, may take even longer to fully remove Pradaxa from their bodies.

Get Help for Your Pradaxa Claim

If you or a loved one took Pradaxa and suffered adverse effects, you may be entitled to compensation. Talk to an attorney from Doyle Raizner today. Our attorneys have extensive experience handling complex injury litigation, and can help evaluate your options.


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